Research

Tissue engineering blood vessels as human grafts and disease models

PRS chondro paper

Selected Publications:

  • Patel B, Wonski BT, Saliganan DM, Rteil A, Kabbani LS, Lam MT. Decellularized dermis extracellular matrix alloderm mechanically strengthens biological engineered tunica adventitia-based blood vessels. Sci Rep. 2021 May 31;11(1):11384.
  • Patel B, Xu Z, Pinnock CB, Kabbani LS, . Self-assembled Collagen-Fibrin Hydrogel Reinforces Tissue Engineered Adventitia Vessels Seeded with Human Fibroblasts. Sci Rep. 2018 Feb 19;8(1):3294.
  • Pinnock CB, Xu Z, . Scaling of Engineered Vascular Grafts using 3D Printed Guides and the Ring Stacking Method. J Vis Exp. (). 2017 Mar 27;(121).
  • Pinnock CB, Meier EM, Joshi N, Wu B, . Customizable Engineered Blood Vessels Using 3D Printed Inserts. Methods (). Guest editors: Anthony Atala & Hooman Sadri-Ardekani. 2016;15(99):20-7.

Stem cells for vascular regeneration

PRS chondro paper

Selected Publications:

  • Lam MT. Mesenchymal Stem Cell Therapies for Skin Repair and Regeneration. Journal of Dermatology & Cosmetology. J Dermat Cosmetol. 2017, 1(3): 00014.
  • Wang L, Meier E, Tian S, Lei I, Liu L, Xian S, , Wang Z. Transplantation of Isl1+ cardiac progenitor cells in small intestinal submucosa improves infarcted heart function. Stem Cell Res Ther. 2017 Oct 16;8(1):230.
  • Meier EM and . Role of mechanical stimulation in stem cell differentiation. JSM Biotechnol Bioeng. 2016, 3(3): 1060.
  • Meier EM, Wu B, Siddiqui A, Tepper DG, Longaker MT, . Mechanical Stimulation Increases RNA-level Expression of Knee Meniscus Genes in Adipose-derived Stromal Cells. Plast Reconstr Surg GO. 2016 16;4(9):e864.

Biomechanics & biomaterials to study and improve vascular engineering

PRS chondro paper

Selected Publications:

  • Xu Z and , “Alginate Application for Heart and Cardiovascular Diseases,” book chapter 14, in Springer Series in Biomaterials Science and Engineering.
  • Volume: Alginates and their Biomedical Applications. Eds: BHA Rehm, F Moradali. Springer. 2016.
  • Zakhem E, Murphy SV, Davis ML, Raghavan S, Lam MT. Introductory Editorial: Image and Video Acquisition and Processing for Clinical Applications. Biomed Eng Comput Biol. 2016:Suppl. 1 35-38.
  • Lam MT, Wu JC. Biomaterials Applications in Cardiovascular Tissue Repair and Regeneration. Expert Review of Cardiovascular Therapy. 2012;10(8):1039-49.